GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Alternative splicing results in four

Alternative splicing results in four transcript variants encoding the same protein

The protein encoded by this gene is involved in cytoskeletal reorganization| vesicle trafficking| endocytosis| and mitosis

|Type IV collagen is the major structural component of glomerular basement membranes (GBM)| forming a 'chicken-wire' meshwork together with laminins| proteoglycans and entactin/nidogen

and a C-terminal region containing multiple XFXFG repeats

GRK 4 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Alternative splicing results in fourGRK4 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. The protein phosphorylates the activated forms of G protein coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene.