PDE11 Rabbit Polyclonal Antibody, 20ul In vitro Transcription Multiple transcript variants have been

Multiple transcript variants have been identified

The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme

The cullin 4B forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell

This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan

PDE11 Rabbit Polyclonal Antibody, 20ul In vitro Transcription Multiple transcript variants have beenThe 3' 5' cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3' 5' cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5' monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical