IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays In a non-canonical activation pathway|

In a non-canonical activation pathway| the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB| inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes

IQGAP3 is a Protein Coding gene

and thus it participates in the death signaling initiated by these receptors

and participates in the MAP kinase-mediated signaling cascade

IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays In a non-canonical activation pathway|This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been