Tak1(Phospho Thr187) Polyclonal Antibody, 100ul Supplements The protein is secreted in

The protein is secreted in plasma where it is a component of very low density lipoprotein

The protease functions in the lysosome to cleave N-terminal tripeptides from substrates

Defects in this gene cause Hailey-Hailey disease

A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified| but it is thought to be non-coding

Tak1(Phospho Thr187) Polyclonal Antibody, 100ul Supplements The protein is secreted inThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP) and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL 1 this protein forms a kinase complex including TRAF6 MAP3K7P1 TAB1 and MAP3K7P2 TAB2; this complex is required for the activation of nuclear factor kappa