Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Mutations in this gene cause

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Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Mutations in this gene causeThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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