PYK2(Phospho Tyr580) Polyclonal Antibody, 20ul Organelle Studies Defects in this gene are

Defects in this gene are frequently found in patients with prostate tumors

structure and immunolocalization data suggest that it may play a role in pre-mRNA processing

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Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus

PYK2(Phospho Tyr580) Polyclonal Antibody, 20ul Organelle Studies Defects in this gene areThis gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and