Phospho-CaSR (T888) Polyclonal Antibody, 20ul Biomatrix The encoded protein contains a

The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity

strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation

there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype

In both human and mouse

Phospho-CaSR (T888) Polyclonal Antibody, 20ul Biomatrix The encoded protein contains aThe protein encoded by CASR (calcium sensing receptor) is a G protein coupled receptor that is expressed in the parathyroid hormone (PTH) producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in