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TPPP Polyclonal Antibody, 100ul Electrophoresis & Labeling a CGG-repeat expansion from 5-22

SKU: 52338652121

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TPPP Polyclonal Antibody, 100ul Electrophoresis & Labeling a CGG-repeat expansion from 5-22Promotes in vitro the polymerization of tubulin into double walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM: Phosphorylated by TPK II. Poor substrate for GSK3.,Belongs to the TPPP family.,subunit: May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with

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Description

a CGG-repeat expansion from 5-22 repeats to 68-450 repeats has been identified in the first intron of this gene

Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and transferase activity

Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate

Expansion of a polyalanine tract and other mutations in this gene cause X-linked mental retardation and epilepsy

TPPP Polyclonal Antibody, 100ul Electrophoresis & Labeling a CGG-repeat expansion from 5-22Promotes in vitro the polymerization of tubulin into double walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM: Phosphorylated by TPK II. Poor substrate for GSK3.,Belongs to the TPPP family.,subunit: May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with

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