ATG7 Rabbit Polyclonal Antibody, 50ul Pipette Controller Mutations in this gene have

Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS)

These products include the cathepsin D light and heavy chains

This protein is a member of the White subfamily and is expressed predominantly in liver tissue

|tissue specificity:Widely expressed| with highest levels in spleen and lung

ATG7 Rabbit Polyclonal Antibody, 50ul Pipette Controller Mutations in this gene haveThis gene encodes an E1 like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53 dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in