SLAP1 Polyclonal Antibody, 100ul Cell Function Analysis Defects in this gene are

Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB)

Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures

This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm

while KIR proteins with the short cytoplasmic domain lack the

SLAP1 Polyclonal Antibody, 100ul Cell Function Analysis Defects in this gene areThe C terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization.,Adapter protein, which negatively regulates T cell receptor (TCR) signaling. Inhibits T cell antigen receptor induced activation of nuclear factor of activated T cells. Involved in the negative