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CD63 Polyclonal Antibody, 100ul[BT-AP01914] Adenovirus Packaging Temperature sensitivity arises from a

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CD63 Polyclonal Antibody, 100ul[BT-AP01914] Adenovirus Packaging Temperature sensitivity arises from aThe protein encoded by CTSZ is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy monopeptidase and carboxy dipeptidase activities. Cathepsin Z has also been known as cathepsin X and cathepsin P. CTSZ is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.

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Description

Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing

An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID:18331714)

resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair

Mutations in this gene are associated with desmin-related myopathy

CD63 Polyclonal Antibody, 100ul[BT-AP01914] Adenovirus Packaging Temperature sensitivity arises from aThe protein encoded by CTSZ is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy monopeptidase and carboxy dipeptidase activities. Cathepsin Z has also been known as cathepsin X and cathepsin P. CTSZ is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.

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