CDCP1(Phospho-Tyr743) Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables AKR1C3 shares high sequence identity

AKR1C3 shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14

GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity

This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes

that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA

CDCP1(Phospho-Tyr743) Rabbit Polyclonal Antibody, 100ul 3D Cell Culture Consumables AKR1C3 shares high sequence identityThis gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene.