Dok-5 Polyclonal Antibody, 100ul Culture Media disease:Defects in MT-ND2 are a

disease:Defects in MT-ND2 are a cause of Leber hereditary optic neuropathy (LHON)

This gene encodes multiple protein isoforms that differ in their inhibitory activity

This gene encodes a nuclear protein involved in homologous recombination| telomere length maintenance| and DNA double-strand break repair

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Dok-5 Polyclonal Antibody, 100ul Culture Media disease:Defects in MT-ND2 are aThe protein encoded by DOK5 (docking protein 5) is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up regulated in patients with systemic sclerosis and