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SPDEF Polyclonal Antibody, 50ul Virus Packaging the encoded protein is tumorigenic

SKU: 53003786596

4.1
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SPDEF Polyclonal Antibody, 50ul Virus Packaging the encoded protein is tumorigenicThe protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen independent transactivator of prostate specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor association than other cancer associated

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Description

the encoded protein is tumorigenic

Transcripts initiating from the downstream promoter encode beta isoforms

It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors

|subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle

SPDEF Polyclonal Antibody, 50ul Virus Packaging the encoded protein is tumorigenicThe protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen independent transactivator of prostate specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor association than other cancer associated

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