IRF-3 Polyclonal Antibody, 50ul[BT-AP04629] Immunoassays LPPs catalyze the dephosphorylation of

LPPs catalyze the dephosphorylation of a number of bioactive lipid mediators that regulate a variety of cell functions

Mutations in TEAD1 cause Sveinsson's chorioretinal atrophy

DUSP7 belongs to a class of DUSPs| designated MKPs| that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795)| JNK (see MIM 601158)| and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins

The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases

IRF-3 Polyclonal Antibody, 50ul[BT-AP04629] Immunoassays LPPs catalyze the dephosphorylation ofIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed