DEAF1 Rabbit Polyclonal Antibody, 50ul Lysosome Mutations in this gene result

Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2

which bind diacylglycerol and phorbol esters

|After shedding| the soluble form (sCD163) may play an anti-inflammatory role| and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions

Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation

DEAF1 Rabbit Polyclonal Antibody, 50ul Lysosome Mutations in this gene resultThis gene encodes a zinc finger domain containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant mental retardation. Alternative splicing results in multiple transcript variants.