LS14A Polyclonal Antibody, 20ul Dialysis IAPP encodes a member of

IAPP encodes a member of the calcitonin family of peptide hormones

There are six pseudogenes of this gene found on chromosomes 2

A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1)| and binds to alpha- and beta-dystrobrevins| which are components of the dystrophin-associated protein complex (DPC)

Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

LS14A Polyclonal Antibody, 20ul Dialysis IAPP encodes a member ofSm like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm like proteins are thought to form a stable heteromer present in tri snRNP particles, which are important for pre mRNA splicing.