LPIN1 Polyclonal Antibody, 50ul In vitro Transcription SIRPA encoded by Tyrosine-protein phosphatase

SIRPA encoded by Tyrosine-protein phosphatase non-receptor type substrate 1 is a member of the signal-regulatory-protein (SIRP) family

inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization

Docking protein 1 encoded by DOK1 is part of a signal transduction pathway downstream of receptor tyrosine kinases

LPIN1 Polyclonal Antibody, 50ul In vitro Transcription SIRPA encoded by Tyrosine-protein phosphataseThis gene encodes a magnesium ion dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator activated receptors to modulate expression of other genes involved