FEN-1 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis Zinc finger DHHC-type containing 15

Zinc finger DHHC-type containing 15 encoded by ZDHHC15 belongs to the DHHC palmitoyltransferase family

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This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner

Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)

FEN-1 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis Zinc finger DHHC-type containing 15Flap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is