DYH5 Rabbit Polyclonal Antibody, 20ul Immune Repertoire Sequencing Disruption of the TGF-beta/SMAD pathway

Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers

Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy

It has a tumor suppressor as well as an oncogenic role in tumor formation

Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body| and plays a regulatory role in chromosome segregation

DYH5 Rabbit Polyclonal Antibody, 20ul Immune Repertoire Sequencing Disruption of the TGF-beta/SMAD pathwayThis gene encodes a dynein protein which is part of a microtubule associated motor protein complex consisting of heavy light and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force generating protein with ATPase activity whereby the release of ADP is thought to produce the force producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3 as well as Kartagener syndrome which are both