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IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis Promotes neuritogenesis in developing hippocampal

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IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis Promotes neuritogenesis in developing hippocampalNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

Promotes neuritogenesis in developing hippocampal neurons

Three alternatively spliced transcript variants encoding the same protein have been described for CPM

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

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IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis Promotes neuritogenesis in developing hippocampalNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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