Rho H Polyclonal Antibody, 100ul Yeast Expression Mutations in this gene result

Mutations in this gene result in cataract congenital nuclear autosomal recessive type 2

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elongins B and C

differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence

Rho H Polyclonal Antibody, 100ul Yeast Expression Mutations in this gene resultThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non Hodgkin's lymphoma occur between this locus and B cell CLL lymphoma 6 (BCL6) on chromosome 3, leading to