PURA1 Rabbit Polyclonal Antibody, 50ul Aspirating Pipets disease:Defects in BRCA1 are a

disease:Defects in BRCA1 are a cause of genetic susceptibility to breast cancer (BC)

This protein may also be a potential biomarker for certain tumors

Additional allele specific isoforms

and inhibit their ability to transactivate by preventing their binding to their DNA response elements

PURA1 Rabbit Polyclonal Antibody, 50ul Aspirating Pipets disease:Defects in BRCA1 are aThis gene encodes a member of the adenylosuccinate synthase family of proteins. The encoded muscle specific enzyme plays a role in the purine nucleotide cycle by catalyzing the first step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP). Mutations in this gene may cause adolescent onset distal myopathy. Alternative splicing results in multiple transcript variants.