SRPK2 Polyclonal Antibody, 20ul Gene Synthesis Mutations resulting in haploinsufficiency for

Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2)

Multiple alternatively spliced transcript variants encoding different isoforms have been observed for MOK

functional protein may be deactivated via cleavage into N-terminal and C-terminal chains

This reaction is calcium dependent

SRPK2 Polyclonal Antibody, 20ul Gene Synthesis Mutations resulting in haploinsufficiency forCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Ser 52 and Ser 588.,Phosphorylates RS domain containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral