STRUM Rabbit Polyclonal Antibody, 100ul Roller Bottles |PTM:Phosphorylated by cyclin A/CDK2

|PTM:Phosphorylated by cyclin A/CDK2

Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer

There is a DQHA (X)2E (X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane

STRUM Rabbit Polyclonal Antibody, 100ul Roller Bottles |PTM:Phosphorylated by cyclin A/CDK2This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin repeat containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive lower