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KCTD3 Rabbit Polyclonal Antibody, 20ul Supplements the C-terminal region of this

SKU: 56278164148

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KCTD3 Rabbit Polyclonal Antibody, 20ul Supplements the C-terminal region of thisThis gene encodes a member of the potassium channel tetramerization domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse this protein interacts with hyperpolarization activated cyclic nucleotide gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants.

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Description

the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase

The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule

The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit

Tissue-specific isoforms that differ at the N-terminus have been described

KCTD3 Rabbit Polyclonal Antibody, 20ul Supplements the C-terminal region of thisThis gene encodes a member of the potassium channel tetramerization domain containing (KCTD) protein family. Members of this protein family regulate the biophysical characteristics of ion channels. In mouse this protein interacts with hyperpolarization activated cyclic nucleotide gated channel complex 3 and enhances its cell surface expression and current density. Alternative splicing results in multiple transcript variants.

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