SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Mutations in this gene cause

Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III)

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways

congenital heart disease and other features

three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Mutations in this gene causePhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.