TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube Alternative splicing of PAX2 results

Alternative splicing of PAX2 results in multiple transcript variants

a leukocyte-specific adaptor protein important for immune cell signaling

contains two regions of tandem immunoglobulin domains on either side of a PEVK region that is rich in proline

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane

TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube Alternative splicing of PAX2 resultsMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.