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4E-BP1 Monoclonal Antibody, 100ul[BT-MCA0093] Antisense Oligonucleotides Defects in SIX1 are a

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4E-BP1 Monoclonal Antibody, 100ul[BT-MCA0093] Antisense Oligonucleotides Defects in SIX1 are aThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

Defects in SIX1 are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3)

the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs

Voltage-dependent calcium channel gamma-7 subunit encoded by CACNG7 is a type II transmembrane AMPA receptor regulatory protein (TARP)

and being expressed in vascular endothelium cells and binding to L-selectin

4E-BP1 Monoclonal Antibody, 100ul[BT-MCA0093] Antisense Oligonucleotides Defects in SIX1 are aThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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