PMEPA1 Polyclonal Antibody, 100ul Cell Proliferation Proteins involved in the first

Proteins involved in the first step of nuclear import have been identified in different systems

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Members of this family are important during development

1987 [PubMed 2446322]

PMEPA1 Polyclonal Antibody, 100ul Cell Proliferation Proteins involved in the firstPMEPA1 encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of PMEPA1 is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of PMEPA1 may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple