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p53 (Mono Methyl Lys370) Polyclonal Antibody, 100ul Liquid Handling &Storage Alternatively spliced transcript variants have

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p53 (Mono Methyl Lys370) Polyclonal Antibody, 100ul Liquid Handling &Storage Alternatively spliced transcript variants haveThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

MIM 179508) have regulatory roles in the formation

PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as

Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified

p53 (Mono Methyl Lys370) Polyclonal Antibody, 100ul Liquid Handling &Storage Alternatively spliced transcript variants haveThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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