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PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates but down regulated in ovarian

SKU: 56986578333

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PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates but down regulated in ovarianThis gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment

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Description

but down regulated in ovarian cancer cell lines and primary carcinomas

Caspases exist as inactive proenzymes composed of a prodomain| a large protease subunit| and a small protease subunit

and the accumulation of insoluble dipeptide repeat protein aggregates that could be pathogenic in FTD-ALS patients (PMID: 23393093)

This protein complex consists of the catalytic subunit Cdc7 associating with the regulatory and activating subunit Dbf4

PEPC(Phospho Ser15) Polyclonal Antibody, 100ul Cell Culture Plates but down regulated in ovarianThis gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment

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