APS Polyclonal Antibody, 50ul Cell Culture This protein and VP16 both

This protein and VP16 both bind to the same site on host cell factor C1

It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface

It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation

This protein may be involved in the onset of pain associated with peripheral neuropathy

APS Polyclonal Antibody, 50ul Cell Culture This protein and VP16 bothThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.