Chk1(Phospho Ser345) Polyclonal Antibody, 20ul Oligo Pool 2-methylacetoacetic acid

2-methylacetoacetic acid

The prototypic member of the family is essential to the biogenesis of connective tissue| encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin

and is a major subunit of positive transcription elongation factor b (p-TEFb)

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

Chk1(Phospho Ser345) Polyclonal Antibody, 20ul Oligo Pool 2-methylacetoacetic acidThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells