FACR1 Rabbit Polyclonal Antibody, 100ul Liquid Handling ＆Storage Sialic acid-binding immunoglobulin-like lectins (SIGLECs)

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily

and to the T-cell activation antigen CD26

Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome

The enzyme also has beta-carboline 2N-methyltransferase activity

FACR1 Rabbit Polyclonal Antibody, 100ul Liquid Handling ＆Storage Sialic acid-binding immunoglobulin-like lectins (SIGLECs)The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction and 16 18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein and studies suggest that the N terminus contains a large catalytic domain located on the outside of the