Calpain 11 Polyclonal Antibody, 20ul Monoclonal Antibody Preparation Class I molecules play a

Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen

which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes

Mutations in BUB1 have been associated with aneuploidy and several forms of cancer

Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis

Calpain 11 Polyclonal Antibody, 20ul Monoclonal Antibody Preparation Class I molecules play aCalpains constitute a family of intracellular calcium dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium dependent signal transduction events during meiosis.