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Dnmt3b Polyclonal Antibody, 50ul Filtration Mutations in SLC9A9 are associated

SKU: 58919109662

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Dnmt3b Polyclonal Antibody, 50ul Filtration Mutations in SLC9A9 are associatedCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated.

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Description

Mutations in SLC9A9 are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder

with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions

it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene

RUNX1 is a transcription factor that regulates the differentiation of hematopoietic stem cells into mature blood cells

Dnmt3b Polyclonal Antibody, 50ul Filtration Mutations in SLC9A9 are associatedCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated.

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