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A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette ATAD3A and ATAD3B (MIM 612317)

SKU: 593992101

4.6
USD141.00 USD162.00

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A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette ATAD3A and ATAD3B (MIM 612317)TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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Description

ATAD3A and ATAD3B (MIM 612317) are mitochondrial membrane proteins that contribute to the stabilization of large mitochondrial DNA (mtDNA)-protein complexes called nucleoids (He et al

this protein acts downstream of JAK kinases

Increased expression of this gene may be linked to psoriasis

Contains 4 ANK repeats

A20 Polyclonal Antibody, 100ul[BT-AP00064] Mechanical Pipette ATAD3A and ATAD3B (MIM 612317)TNFAIP3 was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). TNF alpha induced protein 3 encoded by TNFAIP3 is a zinc finger protein and ubiqitin editing enzyme, and has been shown to inhibit NF kappa B activation as well as TNF mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine mediated immune and inflammatory responses.

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