p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma The encoded protein has six

The encoded protein has six putative transmembrane segments (S1-S6)

enhancing the DNA-binding activity of serum response factor

Paired box transcription factors are important regulators in early development

As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme

p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma The encoded protein has sixThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.