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ErbB-3(Phospho Tyr1328) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds RAN (ras-related nuclear protein) is

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ErbB-3(Phospho Tyr1328) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds RAN (ras-related nuclear protein) isThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the

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Description

RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex

Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation

In addition to mRNA metabolism

The antigen is being used as a target for immunotherapy treatment of human carcinomas

ErbB-3(Phospho Tyr1328) Polyclonal Antibody, 100ul Metabolic enzymes tool compounds RAN (ras-related nuclear protein) isThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the

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