HES1 Polyclonal Antibody, 100ul General Lab Use Mutations in TSC1 have been

Mutations in TSC1 have been associated with tuberous sclerosis

The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations

regulates cytokinesis

where heterozygotes carrying an active paternal allele express the phenotype

HES1 Polyclonal Antibody, 100ul General Lab Use Mutations in TSC1 have beenThis protein belongs to the basic helix loop helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N box rather than the canonical E box.