PUS10 Rabbit Polyclonal Antibody, 50ul Stepper is a 482 amino acid

is a 482 amino acid protein that localizes to the lysosomal membrane and belongs to the CCZ1 family

Gene Ontology (GO) annotations related to this gene include clathrin light chain binding

circadian rhythm

This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor

PUS10 Rabbit Polyclonal Antibody, 50ul Stepper is a 482 amino acidPseudouridination the isomerization of uridine to pseudouridine is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases such as PUS10 catalyze pseudouridination of structural RNAs including transfer ribosomal and splicing RNAs. These enzymes also act as RNA chaperones facilitating the correct folding and assembly of tRNAs (McCleverty