IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 50ul Purification Transcription intermediary factor 1-alpha encoded

Transcription intermediary factor 1-alpha encoded by TRIM24 mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors

It functions as a coreceptor in the process of NK cell activation

and acts as a tumor suppressor in esophageal cancer

Forms ternary complex with RTN4R/NGFR and RTN4R/TNFRSF19

IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody, 50ul Purification Transcription intermediary factor 1-alpha encodedThis gene (IFNGR1) encodes the ligand binding chain (alpha) of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.