HIF-3 Alpha Polyclonal Antibody, 100ul Buffer Solutions Belongs to the peptidase M12A

Belongs to the peptidase M12A family

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease| the regulation of the cellular response to hypoxia and induction of apoptosis

Along with the adhesion and degranulation-promoting adaptor protein

Alternatively spliced transcript variants have been observed for CNOT2

HIF-3 Alpha Polyclonal Antibody, 100ul Buffer Solutions Belongs to the peptidase M12AThe protein encoded by HIF3A (hypoxia inducible factor 3 alpha subunit) is the alpha 3 subunit of one of several alpha beta subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. It is thought that factors containing the alpha 3 subunit are negative regulators of hypoxia