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NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles Two alternative transcripts encoding different

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NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles Two alternative transcripts encoding differentThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several

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Description

Two alternative transcripts encoding different proteins have been described

The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy

GARP complex subunit) encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment

which may play a role in the differentiation of tendon cells and spinal cord interneurons

NCoA-3 Polyclonal Antibody, 20ul[BT-AP11732] Roller Bottles Two alternative transcripts encoding differentThe protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300 CBP associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several

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