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Ku-70 Polyclonal Antibody, 20ul[BT-AP04893] Protein Research This protein is completely inactivated

SKU: 6047929409

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DKK97.20 DKK143.20

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Ku-70 Polyclonal Antibody, 20ul[BT-AP04893] Protein Research This protein is completely inactivatedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

This protein is completely inactivated by EF-2 kinase phosporylation

It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability

Associated with EGFR

Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus

Ku-70 Polyclonal Antibody, 20ul[BT-AP04893] Protein Research This protein is completely inactivatedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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