TBP/TATA Binding Protein Monoclonal Antibody(1F6), 50ul Miscellaneous ovary and peripheral blood leukocytes

ovary and peripheral blood leukocytes

Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP

inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin

It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders

TBP/TATA Binding Protein Monoclonal Antibody(1F6), 50ul Miscellaneous ovary and peripheral blood leukocytesInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA binding protein (TBP) and a group of