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Rb(Phospho Thr826) Polyclonal Antibody, 100ul Cellular Function Assays The encoded protein catalyzes the

SKU: 61001203122

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Rb(Phospho Thr826) Polyclonal Antibody, 100ul Cellular Function Assays The encoded protein catalyzes theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine

resulting in the downregulaton of protein synthesis

The protein encoded by this gene recognizes bacterial flagellin

The protein localizes to plasma membrane ruffles

Rb(Phospho Thr826) Polyclonal Antibody, 100ul Cellular Function Assays The encoded protein catalyzes theThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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