DOC-1 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Isoform 2 is expressed in

Isoform 2 is expressed in all examined tissues except in bone marrow

especially in targeting undruggable diseases like cancer

enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

Several alternatively spliced transcript variants have been described for this gene

DOC-1 Polyclonal Antibody, 100ul Nucleic Acid Isolation & Purification Isoform 2 is expressed inCyclin dependent kinase 2 associated protein 1encoded by CDK2AP1 is a cyclin dependent kinase 2 (CDK2) associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S phase of the