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CDKN3 Polyclonal Antibody, 100ul[BT-AP07568] 3D Cell Culture Consumables The protein encoded by IGFALS

SKU: 61667295006

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CDKN3 Polyclonal Antibody, 100ul[BT-AP07568] 3D Cell Culture Consumables The protein encoded by IGFALSThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this

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Description

The protein encoded by IGFALS is a serum protein that binds insulin-like growth factors

|tissue specificity:Isoform 1 is strongly expressed in the liver

It activates E-box dependent transcription along with E47

This PTP was thought to play roles in cell-cell recognition and adhesion

CDKN3 Polyclonal Antibody, 100ul[BT-AP07568] 3D Cell Culture Consumables The protein encoded by IGFALSThe protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this

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